{"id":229,"date":"2014-11-14T07:50:56","date_gmt":"2014-11-14T07:50:56","guid":{"rendered":"http:\/\/www.biobridge-event.com\/knowledge\/2014\/11\/14\/prof-jean-paul-meningaud-conversion-of-a-full-department-of-a-public-hospital-to-regenerative-medicine\/"},"modified":"2019-01-14T12:51:20","modified_gmt":"2019-01-14T11:51:20","slug":"prof-jean-paul-meningaud-conversion-of-a-full-department-of-a-public-hospital-to-regenerative-medicine","status":"publish","type":"post","link":"https:\/\/library.biobridge-event.com\/knowledge\/2014\/11\/14\/prof-jean-paul-meningaud-conversion-of-a-full-department-of-a-public-hospital-to-regenerative-medicine\/","title":{"rendered":"Prof. Jean-Paul Meningaud &#8211; \u201cConversion of a full department of a public hospital to Regenerative Medicine\u201d"},"content":{"rendered":"<div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-1 hundred-percent-fullwidth non-hundred-percent-height-scrolling\"  style='background-color: rgba(255,255,255,0);background-position: center center;background-repeat: no-repeat;padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;'><div class=\"fusion-builder-row fusion-row \"><div  class=\"fusion-layout-column fusion_builder_column fusion_builder_column_1_1 fusion-builder-column-1 fusion-one-full fusion-column-first fusion-column-last fusion-column-no-min-height 1_1\"  style='margin-top:0px;margin-bottom:0px;'>\n\t\t\t\t\t<div class=\"fusion-column-wrapper\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;\"   data-bg-url=\"\">\n\t\t\t\t\t\t\n<div class=\"video-shortcode\">\n<div class=\"embed-vimeo\" style=\"text-align: center;\"><iframe src=\"https:\/\/player.vimeo.com\/video\/111820857\" width=\"1100\" height=\"619\" frameborder=\"0\" webkitallowfullscreen mozallowfullscreen allowfullscreen><\/iframe><\/div>\n<\/div>\n<p>The development of surgical adjuvants to potentiate wound healing and decrease major surgical complications<br \/>\nis one of the great challenges of clinical research in our department.<\/p>\n<p>In our routine practice, both autologous PRP and autologous PRP glue (RegenPRP \/RegenKit\u00ae) were applied<br \/>\nin plastic and reconstructive surgery, and the application can be divided into three major axes: reconstructive<br \/>\nsurgery, wound healing and cosmetic treatment.<\/p>\n<p>In soft tissue reconstruction, supplementing of lipofiling with autologous PRP can improve the survival of fat<br \/>\ngrafts and provides satisfactory outcomes. This preparation is routinely used in different conditions including<br \/>\nbreast, calf, genitalia augmentation and filling defect such as hemifacial atrophy. For the management of<br \/>\nburn scars, a new protocol will be established in our department involving the use of dermabrasion, dermal<br \/>\ninjections of PRP combined to lipofiling to improve the trophicity of skin and spraying of keratinocytes<br \/>\nsuspension combined to PRP.<\/p>\n<p>By improving haemostasis and tissue adherence, autologous PRP glue is used to prevent hematoma and seroma formation after breast reduction, abdominoplasty, brachioplasty, bodylift, cruroplasty and rhytidectomy.<br \/>\nIndeed, autologous PRP glue is often used to accelerate wound healing and improve the success of skin<br \/>\ngrafts in recalcitrant healing (chronic and acute wound). In a preliminary study, the use of PRP glue combined<br \/>\nwith skin graft surgery in the management of patients with necrotizing soft tissue infection showed that the<br \/>\naverage of hospitalisation time after debridement and reconstruction procedures is 8.67 days (n= 8) compared<br \/>\nto control without PRP glue 13.87 days (n=8). These results show that autologous-PRP glue appeared to<br \/>\nincrease skin graft success and accelerate wound healing in the context of post-infectious cutaneous defect.<br \/>\nIn cosmetic treatment, injection of autologous PRP combined to hyaluronic acid is used for volume restoration<br \/>\nand on mesotherapy in the face rejuvenation.<\/p>\n<p>These works thus make it possible to plan many future applications for the PRP and showed the interest<br \/>\nof PRP as surgical adjuncts to enhance wound healing, reduce incidences of complications and length of<br \/>\nhospital stay. In this context, a multi-centre clinical trial will be conducted in four European countries. The<br \/>\nstudy \u201cNEWSKIN\u201d address the management of patients with skin defects, and involve the development of<br \/>\nan innovative surgical procedure using autologous tissues and cells to reconstruct the three layers of skin<br \/>\n(hypodermis, dermis, epidermis).<div class=\"fusion-clearfix\"><\/div>\n\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div><\/div><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":6,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_bbp_topic_count":0,"_bbp_reply_count":0,"_bbp_total_topic_count":0,"_bbp_total_reply_count":0,"_bbp_voice_count":0,"_bbp_anonymous_reply_count":0,"_bbp_topic_count_hidden":0,"_bbp_reply_count_hidden":0,"_bbp_forum_subforum_count":0,"_mi_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"_price":"","_stock":"","_tribe_ticket_header":"","_tribe_default_ticket_provider":"","_tribe_ticket_capacity":"0","_ticket_start_date":"","_ticket_end_date":"","_tribe_ticket_show_description":"","_tribe_ticket_show_not_going":false,"_tribe_ticket_use_global_stock":"","_tribe_ticket_global_stock_level":"","_global_stock_mode":"","_global_stock_cap":"","_tribe_rsvp_for_event":"","_tribe_ticket_going_count":"","_tribe_ticket_not_going_count":"","_tribe_tickets_list":[],"_tribe_ticket_has_attendee_info_fields":false,"spay_email":""},"categories":[8,6],"tags":[20,4,28,21],"aioseo_notices":[],"jetpack_featured_media_url":"","jetpack_shortlink":"https:\/\/wp.me\/pawNNh-3H","jetpack_likes_enabled":true,"_links":{"self":[{"href":"https:\/\/library.biobridge-event.com\/knowledge\/wp-json\/wp\/v2\/posts\/229"}],"collection":[{"href":"https:\/\/library.biobridge-event.com\/knowledge\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/library.biobridge-event.com\/knowledge\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/library.biobridge-event.com\/knowledge\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/library.biobridge-event.com\/knowledge\/wp-json\/wp\/v2\/comments?post=229"}],"version-history":[{"count":1,"href":"https:\/\/library.biobridge-event.com\/knowledge\/wp-json\/wp\/v2\/posts\/229\/revisions"}],"predecessor-version":[{"id":3547,"href":"https:\/\/library.biobridge-event.com\/knowledge\/wp-json\/wp\/v2\/posts\/229\/revisions\/3547"}],"wp:attachment":[{"href":"https:\/\/library.biobridge-event.com\/knowledge\/wp-json\/wp\/v2\/media?parent=229"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/library.biobridge-event.com\/knowledge\/wp-json\/wp\/v2\/categories?post=229"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/library.biobridge-event.com\/knowledge\/wp-json\/wp\/v2\/tags?post=229"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}